Verifira Order
Class

Mitochondrial and cell-ageing compounds

Research use only. Not for human or veterinary consumption. 18+.

Compounds studied at the level of the mitochondrion and of cellular ageing. Two are peptides encoded in mitochondrial DNA or targeted to the inner mitochondrial membrane; the rest are grouped by the same field of study rather than by structure.

What this class is

MOTS-C is a 16-residue peptide encoded within the mitochondrial 12S rRNA gene, one of a small number of known mitochondrial-derived peptides. SS-31, elamipretide, is a tetrapeptide that concentrates at the inner mitochondrial membrane by binding cardiolipin. Epithalon is a synthetic tetrapeptide based on a pineal extract. FOXO4-DRI is a retro-inverso peptide built from D-amino acids in reverse sequence, designed to disrupt a FOXO4-p53 interaction. NAD+ is not a peptide at all but a nucleotide coenzyme, included here because it belongs to the same area of study.

5 in this class

Research use only. Not for human or veterinary consumption. 18+.

Research use only. Not for human or veterinary consumption. 18+.

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